GETTING MY FRACTAL STORM (SELF-LAID TO WORK

Within the LSD-bound crystal construction, the facet chain in the lid residue L209EL2 forms in depth hydrophobic contacts with both equally LSD and surrounding residues in TMs III, IV, and V (Figure 4C). If the lid moved apart to show the binding pocket in simulation, a number of of such contacts broke. We thus hypothesized that L209EL2 acts for a